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NFL Week 6 odds: Moneylines, point spreads, over/under
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Date:2025-04-21 15:44:49
Six weeks into the season, teams are starting to pull away as championship contenders and others are falling into top-draft pick talk.
There are two undefeated teams left. And they're both in the NFC.
The Philadelphia Eagles (5-0) take on the New York Jets (2-3), who are flying high after a personal win over the Denver Broncos (1-4) last week.
The San Francisco 49ers (5-0) face the Cleveland Browns (2-2), who will be fresh off their bye week. The 49ers are favorites on the road after their handling of the Dallas Cowboys (3-2).
Week 6 opens on Thursday night featuring one of the top teams in the AFC as the Kansas City Chiefs (4-1) host the lowly Broncos. The defending Super Bowl champions are the favorites to win, even as Taylor Swift might be done making her appearances.
NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.
The Miami Dolphins (4-1) host the only winless team left in the league, the Carolina Panthers (0-5). Mike McDaniel and his high-powered offense are favored as rookie Bryce Young continues to find his footing.
The Green Bay Packers (2-3) and Pittsburgh Steelers (3-2) have byes this week.
If you’re new to sports betting, don’t worry. We have tips for beginners on how to place bets online. And USA TODAY readers can claim exclusive promos and bonus codes with the online sportsbooks and sports betting sites.
NFL STATS CENTRAL: The latest NFL scores, schedules, odds, stats and more.
Here are the NFL betting odds for Week 6, according to the BetMGM NFL odds.
NFL Week 6 picks/predictions
- Denver Broncos at Kansas City Chiefs
- Baltimore Ravens at Tennessee Titans in London
- Washington Commanders at Atlanta Falcons
- Minnesota Vikings at Chicago Bears
- Seattle Seahawks at Cincinnati Bengals
- San Francisco 49ers at Cleveland Browns
- New Orleans Saints at Houston Texans
- Indianapolis Colts at Jacksonville Jaguars
- Carolina Panthers at Miami Dolphins
- New England Patriots at Las Vegas Raiders
- Detroit Lions at Tampa Bay Buccaneers
- Arizona Cardinals at Los Angeles Rams
- Philadelphia Eagles at New York Jets
- New York Giants at Buffalo Bills
- Dallas Cowboys at Los Angeles Chargers
NFL Week 6 point spreads
- Denver Broncos (+10.5) at Kansas City Chiefs (-10.5)
- Baltimore Ravens (-4) at Tennessee Titans (+4) in London
- Washington Commanders (+2.5) at Atlanta Falcons (-2.5)
- Minnesota Vikings (-2.5) at Chicago Bears (+2.5)
- Seattle Seahawks (+3) at Cincinnati Bengals (-3)
- San Francisco 49ers (-6) at Cleveland Browns (+6)
- New Orleans Saints (-1.5) at Houston Texans (+1.5)
- Indianapolis Colts (+4) at Jacksonville Jaguars (-4)
- Carolina Panthers (+13.5) at Miami Dolphins (-13.5)
- New England Patriots (+3) at Las Vegas Raiders (-3)
- Detroit Lions (-3) at Tampa Bay Buccaneers (+3)
- Arizona Cardinals (+7) at Los Angeles Rams (-7)
- Philadelphia Eagles (-7) at New York Jets (+7)
- New York Giants (+14) at Buffalo Bills (-14)
- Dallas Cowboys (-2) at Los Angeles Chargers (+2)
NFL Week 6 moneylines
- Denver Broncos (+425) at Kansas City Chiefs (-600)
- Baltimore Ravens (-200) at Tennessee Titans (+165) in London
- Washington Commanders (+110) at Atlanta Falcons (-145)
- Minnesota Vikings (-145) at Chicago Bears (+120)
- Seattle Seahawks (+135) at Cincinnati Bengals (-160)
- San Francisco 49ers (-275) at Cleveland Browns (+225)
- New Orleans Saints (-125) at Houston Texans (+105)
- Indianapolis Colts (+165) at Jacksonville Jaguars (-200)
- Carolina Panthers (+575) at Miami Dolphins (-900)
- New England Patriots (+145) at Las Vegas Raiders (-175)
- Detroit Lions (-165) at Tampa Bay Buccaneers (+135)
- Arizona Cardinals (+240) at Los Angeles Rams (-300)
- Philadelphia Eagles (-300) at New York Jets (+240)
- New York Giants (+575) at Buffalo Bills (-900)
- Dallas Cowboys (-130) at Los Angeles Chargers (+110)
NFL Week 6 over/under
- Denver Broncos at Kansas City Chiefs: 47.5
- Baltimore Ravens at Tennessee Titans in London: 41
- Washington Commanders at Atlanta Falcons: 42.5
- Minnesota Vikings at Chicago Bears: 44.5
- Seattle Seahawks at Cincinnati Bengals: 45.5
- San Francisco 49ers at Cleveland Browns: 37.5
- New Orleans Saints at Houston Texans: 42.5
- Indianapolis Colts at Jacksonville Jaguars: 45.5
- Carolina Panthers at Miami Dolphins: 48.5
- New England Patriots at Las Vegas Raiders: 41.5
- Detroit Lions at Tampa Bay Buccaneers: 44
- Arizona Cardinals at Los Angeles Rams: 48.5
- Philadelphia Eagles at New York Jets: 41
- New York Giants at Buffalo Bills: 44.5
- Dallas Cowboys at Los Angeles Chargers: 50.5
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